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Job Description
As an Associate Scientist / Engineer 1 in Illumina’s Array Development Group, you will play an integral role in developing next generation –omic Array based assays for diverse research and applied markets.
You will work as part of a fast paced, multi-disciplinary team focused on the enhancement of current, and development of new biochemical assays to understand the presence of different -omic traits on Illumina’s proprietary BeadArray technology.
Job Responsibilities:
- Develop, characterize and optimize assay protocols and HW.
- Recognize potential problems, understand and troubleshoot assays and associated HW.
- Plan, conduct, analyze, interpret, and report recommendations based on tested experimental results.
- Conduct experiments and analyze data to support a robust supply of key components of the Infinium Assay.
- Develop analytical test methods to QC and understand capability of assay HW, and consumable components accurately and precisely.
- Develop hypothesis and statistically relevant data sets to prove correlations between physical and biochemical metrics.
- Analyze large complex data sets with statistical methodology.
- Participate in fast paced multidisciplinary development and troubleshooting teams.
- Conduct focused research under general direction of supervisor and drive projects.
- Support the testing of new Array scanner and assay automation software.
- Keep a laboratory notebook, write reports and prepare presentations.
- Become an expert in Illumina’s BeadArray assays including, but not limited to, Infinium Genotyping, Methylation, and Copy number variation.
- Deliver results in a fast-paced, results orientated, product development environment.
- Perform other duties as assigned.
Qualifications
Required Skills and Experience:
- MSc or BSc in Bioengineering, Chemistry (analytical /physical), Biochemistry, Mechanical Engineering or related field with a minimum 7 years’ working experience in an industrial laboratory.
- PhD in Bioengineering, Chemistry (analytical /physical), Biochemistry, molecular biology or related field with an applied or application specific focus and a minimum 1 year of industrial experience.
- Demonstrated ability to develop analytical test methods to quantify inputs and outputs of key process steps.
- Hands-on experience with development and optimization of workflow / HW for biochemical assays.
- Demonstrated ability to develop QC test methods to validate HW for genomic assays.
- Practical experience with design, planning and execution of system / workflow level verification and validation.
- Practical experienced with physical characterization metrology (topology, surface energy, fluid dynamics etc).
- Proven record of troubleshooting assay processes to deliver root cause and robust fixes.
- Experienced in molecular biology methods for nucleic acid analysis and manipulation including purification, amplification, labeling, hybridization for both DNA and RNA.
- Excellent verbal/written communication and interpersonal skills.
- Flexible and adaptable.
- Analytical, detail-oriented, organized, takes initiative, and self-motivated.
- Record of process driven approach to experimental design and troubleshooting, including understanding of DOE and statistical analysis / scripting software such as JMP and R.
- Technical understanding of SNP genotyping analysis tools a benefit.
- Excellent lab notebook and documentation skills.
Preferred Skills and Experience:
Additional Information
All your information will be kept confidential according to EEO guidelines.
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