Engineer I/II, LNP Process Development Somerville, Massachusetts, United States

Somerville, Massachusetts, United States

Minimum Qualifications

• A Bachelor's degree in Chemical Engineering, Bioengineering, or Biological Sciences and 0-4 years of experience, or a Master's degree in these fields with 0-2 years of experience.
• A track record of planning experiments and completing deliverables within specified timelines.
• Excellent communication/presentation skills and capability of conveying technical information in a clear and thorough manner.
• A strong self-starter with excellent organizational skills and a strong attention to detail.
• The ability to work with dynamic teams in a fast-paced, entrepreneurial, and technical setting.
• Proficiency in MS Office.
• It's a bonus if you have:
  • Prior experience working with lipid nanoparticles in a process development or manufacturing context.
  • Experience with tangential flow filtration (TFF) process development.
  • Experience with JMP or Prism.

Responsibilities

• Assisting with experimental design and execution of different downstream unit operations including mixing, tangential flow filtration, and sterile filtration.
• Performing characterization of LNPs to determine size, polydispersity, concentration and encapsulation using established techniques.
• Executing experimental plans and interpreting the results with guidance from senior scientists.
• Troubleshooting lab workflows and maintaining lab equipment.
• Providing high quality results and maintaining high quality documentation in lab notebooks.
• Assisting in development of in-house LNP production capabilities to supply high quality LNP for pre-clinical and platform development.
• Collaborating effectively with manufacturing team and analytical development teams.
• Drafting protocols and technical reports and presenting to stakeholders.

About You

You are a driven, enthusiastic and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. You are interested in joining a dynamic and highly collaborative team that's responsible for the design, scale, and implementation of mRNA Lipid Nanoparticle (LNP) production processes.

Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence.

Company Summary

Tessera Therapeutics is pioneering Gene Writing— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

Equal Opportunity Employer

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities.