Senior Engineer I/II, Computational Biology

Your experience includes...

• Bachelor of Science in computer science, data science, or related field with 5+ years of experience (or Masters/3+, PhD) applying an engineering discipline to biomedical research, biotechnology, or computational biology at a scientific research institute or in thebiotechnology industry.
• Proficiency in using Python or another modern programming language
• Proficiency in SQL and experience in data modeling and database design.
• Cloud-based software solutions (AWS preferred) and orchestration/integration software (e.g. Dagster, Nextflow). Knowledge of Docker.
• Software development skills including source control systems and integration/deployment strategies.
• It's a bonus if you have:
  • Understanding of data management best practices as it relates to biological data.
  • Understanding of modern principles of data analysis as it pertains to computational biology
  • Experience with lab software Benchling (electronic lab notebooks).
  • Experience with project management tools to track activities (Jira) and create documentation of deliverables (Confluence).

You are interested in...

• Designing and developing databases to store large volume data, to be queried in high-performance and cloud environments.
• Developing queries to internal genomic databases to answer specific biological questions and generate new hypotheses.
• Developing computational biology pipelines with leading cloud technologies (i.e. Dagster, Nextflow) and state-of-the-art control systems software and procedures (i.e. CI/CDs, unit tests, etc.).
• Becoming part of a dynamic, expanding team in a fast-paced and supportive environment with different groups and experts from various backgrounds.
• It's a bonus if you have an analytical interest in developing computational biology analyses together with the Computational Biology team of scientists.

About you:
As part of the Computational Biology team within the Data Science department, you will lead the engineering efforts designed by Computational Biologists to solve targeted scientific biological questions. You will closely collaborate with Data Engineering and Software Engineering teams to deploy your solutions on AWS. Your expertise will be critical for integrating the technologies we use and developing strategic tools that support our research in clinical investigations. Additionally, you will apply your knowledge to create comprehensive documentation of your procedures and processes.
Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to excellence.
Meet your Manager:
All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.
Andrea Calabria - Director, Computational Sciences
Andrea is an engineer by education (B.Sc. and M.Sc.) at the Polytechnic of Milan (Italy) and obtained his Ph.D. in Computer Science from the University of Milan Bicocca (Italy) in the field of computational biology. He spent 11 years after Ph.D. in the field of Gene Therapy at San Raffaele Telethon Institute for Gene Therapy of Milan (Italy), becoming a recognized researcher (his H-index is 24, ORCID working on safety and insertional mutagenesis assessment of gene therapy treatments with viral vectors and dissecting hematopoietic stem cell differentiation in vivo in human with clonal dynamics. He joined Tesera in 2023, leading the team of computational biology with the responsibilities of supporting all the genotox packages for our drug candidates and new molecular assay developments.
Meet our Leadership Team and Board of Directors
Meet your Talent Partner:
Narissa Furtado-Cordeiro - Manager, Talent Acquisition
Narissa joined the Biotechnology industry shortly after graduating with her BS in Marketing from Franklin Pierce University. She is currently pursuing a MS in Legal Studies from Northeastern University School of Law while working full time as a Manager in Talent Acquisition at Tessera. She is passionate about helping individuals find a fulfilling opportunity while considering their interests, aspirations and technical skills. Narissa lives in Northern Vermont and enjoys spending time outdoors with her husband, three-year-old daughter and German Shepherd.
Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
More about Tessera Therapeutics:
Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or
Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics' internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.